Selected Publications:
2024
Lindell RB, Sayed S, Campos JS, Knight M, Mauracher AA, Hay CA, Conrey P, Fitzgerald JC, Yehya N, Famularo ST, Arroyo T, Tustin R, Fazelinia H, Behrens EM, Teachey DT, Freeman AF, Bergerson JRE, Holland SM, Leiding JW, Weiss SL, Hall MW, Zuppa AF, Taylor D, Feng R, Wherry EJ, Meyer NJ, Henrickson SE. Dysregulated STAT3 signaling and T cell immunometabolic dysfunction define a targetable, high mortality subphenotype of critically ill children. medRxiv. 2024 Jun 10. [DOI: 10.1101/2024.06.11.24308709]
Lindell RB, Meyer NJ. “Charting a Course for Precision Sepsis Trials.” Lancet Respir Med. 2024 Apr;12(4):265-267. [PMID: 38484747] [DOI: 10.1016/S2213-2600(24)00070-5]
Campos JS, Sayed S, Dalalo MC, Mauracher AA, Knight MS, Conrey PE, Schultz AB, Hay CA, Lindell RB, Howard CA, Abrams ED, Schmitt EG, Thelin M, Bluestein S, Canna SW, Su HC, Keller MD, Delmonte OM, Forbes Satter LR, Holland SM, Bergerson JRE, Leiding JW, Romberg ND, Freeman AF, Villarino AV, Anderson MS, Cooper MA, Vogel TP, Henrickson SE. Altered Purinergic Signaling and CD8+ T Cell Dysregulation in STAT3 GOF Syndrome. bioRxiv. 2024 Dec 13. [DOI: 10.1101/2024.12.12.626682]
Banigan M, Keim GP, Traynor D, Yehya N, Lindell RB, Fitzgerald JC. Association of Continuous Kidney Replacement Therapy Timing and Mortality in Critically Ill Children. Pediatr Nephrol. 2024 Feb 23. Online ahead of print. [PMID: 38396090] [DOI: 10.1007/s00467-024-06320-w]
2023
Lindell RB, Meyer NJ. Interrogating the sepsis host response using cytomics. Crit Care. 2023 Mar 21;27(1):93. [PMID: 36941659] [PMCID: PMC10027588] [DOI: 10.1186/s13054-023-04366-0]
Nguyen J, Thompson JM, Balcarcel DR, Wong HR, Alder MN, McKeone DJ, Halstead ES, Rowan CM, Lindell RB, Yehya N. Immunocompromised children with ARDS possess a distinct circulating inflammatory profile. Crit Care Explor. 2023 Jan 6;5(1):e0844. [PMID: 36699254] [PMCID: PMC9829269] [DOI: 10.1097/cce.0000000000000844]
Lenz KB, Nishisaki A, Lindell RB, Yehya N, Laverriere E, Bruins BB, Napolitano N, McGowan N, Traynor DM, Rowan CM, Fitzgerald JC. Peri-intubation adverse events in the critically ill child after hematopoietic cell transplant. Pediatr Crit Care Med. 2023 Jul 1;24(7):584-593. [PMID: 37098779] [PMCID: PMC10330041] [DOI: 10.1097/pcc.0000000000003243]
2022
Lindell RB, Fitzgerald JC, Rowan CW, Flori HR, Di Nardo M, Napolitano N, Traynor DM, Lenz KB, Emeriaud G, Jeyapalan A, Nishisaki A. Duration of pre-intubation respiratory support is associated with increased mortality in immunocompromised children with respiratory failure. Crit Care Med. 2022 Jul 1;50(7):1127-1137. [PMID: 35275593] [PMCID: PMC9707852] [DOI: 10.1097/CCM.0000000000005535]
Lindell RB, Zhang D, Bush J, Wallace DC, Rabinowitz JD, Lu W, Wherry EJ, Weiss SL, Henrickson SE. Impaired lymphocyte responses in pediatric sepsis vary by pathogen type and are associated with features of immunometabolic dysregulation. Shock. 2022 Jun 1;57(6):191-199. [PMID: 35759301] [PMCID: PMC9245144] [DOI: 10.1097/SHK.0000000000001943]
Weiss SL, Henrickson SE, Lindell RB, Sartori LF, Zhang D, Bush J, Farooqi S, Starr J, Deutschman CS, McGowan FX, Becker L, Tuluc F, Wherry EJ, Picard M, Wallace DC. Influence of Immune Cell Subtypes on Mitochondrial Measurements in Peripheral Blood Mononuclear Cells from Children with Sepsis. Shock. 2022 May 1;57(5):630-638. [PMID: 34966070] [PMCID: PMC9117409] [DOI: 10.1097/SHK.0000000000001903]
Diorio C, Shraim R, Myers RM, Behrens EM, Canna S, Bassiri H, Aplenc R, Burudpakdee C, DiNofia AM, Gill S, Glisovic-Aplenc T, Gonzalez VE, Lambert M, Leahy AB, Levine BL, Lindell RB, Maude SL, Melenhorst JJ, Newman H, Perazzelli J, Seif AE, Lacey SF, June CH, Barrett DM, Grapp SA, Teachey DT. Comprehensive Serum Proteome Profiling of Cytokine Release Syndrome and Immune Effector Cell Associated Neurotoxicity Syndrome in Patients Receiving CART19. Clin. Cancer Res. 2022 Sep 1;28(17):3804-3813. [PMID: 35705524] [PMCID: PMC9444956] [DOI: 10.1158/1078-0432.ccr-22-0822]
2021
Lindell RB, Wolf MS, Alcamo AM, Silverman MA, Dulek DE, Otto WR, Olson TS, Kitko CL, Paueksakon P, Chiotos K. Immune dysregulation due to Toxoplasma gondii reactivation after allogeneic hematopoietic cell transplant: a case series and review of the literature. Front. Pediatr. 2021 Aug 10;9:719679. [PMID: 34447731] [PMCID: PMC8382793] [DOI: 10.3389/fped.2021.719679]
Meyer NJ, Lindell RB, Wherry EJ. Immune Stimulation with Recombinant Human Granulocyte Colony-Stimulating Factor for Coronavirus Disease 2019 (COVID-19) – Beware of Blind Spots. JAMA Intern. Med. 2021 Jan 1;181(1):78-80. [PMID: 32910155] [DOI: 10.1001/jamainternmed.2020.5536]
Tsukahara K, Lindell RB, Newman H, Lerman BJ, Kersun LS, Piccione J. Successful whole lung lavage in a child with pulmonary alveolar proteinosis secondary to hematologic malignancy. Pediatr Pulmonol. 2021 Oct 13. [PMID: 34644455] [PMCID: PMC8665118] [DOI: 10.1002/ppul.25718]
2020
Lindell RB, Nishisaki A, Weiss SL, Traynor DM, Fitzgerald JC. Risk of mortality in immunocompromised children with severe sepsis and septic shock. Crit Care Med. 2020 Jul;48(7):1026-1033. [PMID: 32301846] [PMCID: PMC7311286] [DOI: 10.1097/CCM.0000000000004329]